For centuries, vampires and werewolves have waged a secret war in the shadows of the city. Selene, a lethal vampire warrior specialized in hunting werewolves to avenge her family, discovers that they are pursuing with unusual persistence Michael, a young human oblivious to the conflict. As she feels drawn to him, she begins to unearth a conspiracy that threatens the foundations of her own clan and rewrites everything she believed she knew about this age-old war. Gothic action cinema of cold, bluish style, fusing the vampire myth with the supernatural thriller.