Melissa Jaffer (born December 1, 1936) is an Australian actress. She is best known for her television roles, but has also appeared in many Australian films.

Jaffer has made many appearances in television series, including Kings, Mother and Son, G. P., Brides of Christ, Grass Roots and All Saints. Jaffer is probably best known to international audiences for her role as aging mystic Utu-Noranti Pralatong in the science fiction series Farscape. In 1976, Jaffer tied for the first AACTA Award for Best Actress in a Supporting Role opposite Jacki Weaver for her performance in Caddie. In 1980 she played the part of Cousin Edie in the Australian Broadcasting Corporation's children's television series The Nargun and the Stars.

In the 2015 film Mad Max: Fury Road she played the role of "Keeper of the Seeds". The short film Dear Life is her latest project.