Curtis Hanson's warm-hearted drama, adapted from Jennifer Weiner's novel, follows two mismatched sisters, a responsible lawyer (Toni Collette) and her irresponsible, dyslexic party-girl sibling (Cameron Diaz), whose estrangement leads the younger one to a grandmother (Shirley MacLaine) she never knew. Wiser and more affecting than its chick-flick packaging suggested, it's a nuanced study of family, self-worth and the poems of Elizabeth Bishop, elevated by strong performances all around.