Melis Birkan (born 15 July 1982) is a Turkish actress. She graduated from ballet department for elementary school, high school and modern dance department for university in State Conservatory of Mimar Sinan Fine Arts University. She is best known for theatre and films Issız Adam, Barda, Sen Ben Lenin, Ulak, Adını Sen Koy. She won Sadri Alışık Best Actress Award for Issız Adam.

She was cast in romantic comedy series in "Çapkın" alongside Okan Yalabık. With Erdal Beşikçioğlu, she was cast in "Köprü" based on life of governor Recep Yazıcıoğlu. She had guest roles in hit comedies Avrupa Yakası and İşler Güçler.

With Okan Yalabık, she played in spin off period series Bu Kalp Seni Unutur mu? of hit series Hatırla Sevgili. She played in period comedy drama series in "Deli Saraylı" with ensemble cast.

She joined as leading role in third season of hit surreal comedy Leyla ile Mecnun. She played in hit mini series 46: Yok Olan alongside Erdal Beşikçioğlu again.

With Tolga Sarıtaş, she played in mini historical series Büyük Sürgün Kafkasya about Meskhetian Turks and in third season of military series Söz which nominated International Emmy Awards.